Bdnf^tm1.1Meg
Targeted Allele Detail

Summary

• Symbol: Bdnf^tm1.1Meg
• Name: brain derived neurotrophic factor; targeted mutation 1.1, Micheal E Greenberg
• MGI ID: MGI:3809491
• Synonyms: Bdnf pIV^-, BdnfpIV^-, Bdnf^tm1Meg
• Gene: Bdnf Location: Chr2:109505045-109557352 bp, + strand Genetic Position: Chr2, 56.63 cM
• Alliance: Bdnf^tm1.1Meg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:139381
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv

Mutation description

• Allele Type: Targeted (Modified isoform(s), Modified regulatory region)
• Mutation: Intragenic deletion
• Find Mice (IMSR):
  • Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
  • Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
  • Carrying any Bdnf Mutation: 42 strains or lines available
• References:
  • Original: J:139381 Singh KK, et al., Developmental axon pruning mediated by BDNF-p75NTR-dependent axon degeneration. Nat Neurosci. 2008 Jun;11(6):649-58
  • All: 2 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 03/18/2025 MGI 6.24