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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Camk2a-Crem)I15Endo
transgene insertion I15, Shogo Endo
MGI:3802596
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
tg1
Tg(Camk2a-Crem)I15Endo/0 involves: C3H * C57BL/6 MGI:3803753


Genotype
MGI:3803753
tg1
Allelic
Composition
Tg(Camk2a-Crem)I15Endo/0
Genetic
Background
involves: C3H * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Camk2a-Crem)I15Endo mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• despite altered conditioning memory, mice exhibit normal odor discrimination memory
• mice display an attenuated freezing response 24 hours after conditioning compared to wild-type mice
• however, short-term conditioning is normal
• mice display an attenuated freezing response 24 hours after conditioning compared to wild-type mice
• however, short-term conditioning is normal
• in low or bright light conditions, mice spend more time in the center of an open field compared to wild-type mice
• mice exhibit reduced time fall compared to wild-type mice on a hanging wire test
• during the dark phase
• mice take longer to develop more profound seizures and fewer mice reach full kindling compared to similarly treated wild-type mice
• however, afterdischarge duration during kindling is normal

nervous system
• mice take longer to develop more profound seizures and fewer mice reach full kindling compared to similarly treated wild-type mice
• however, afterdischarge duration during kindling is normal





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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory