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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Kat2atm3.2Roth
targeted mutation 3.2, Sharon Y R Dent
MGI:3801276
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Kat2atm3.2Roth/Kat2atm3.2Roth involves: 129 MGI:3801318
ht2
 		Kat2atm1Roth/Kat2atm3.2Roth involves: 129/Sv * 129S7/SvEvBrd MGI:3801319
cn3
 		Kat2atm3.1Roth/Kat2atm3.2Roth
Tg(Pcp2-cre)2Mpin/0 		involves: 129 MGI:5315468


Genotype
MGI:3801318
hm1
Allelic
Composition		 Kat2atm3.2Roth/Kat2atm3.2Roth
Genetic
Background		 involves: 129
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kat2atm3.2Roth mutation (1 available); any Kat2a mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:132940 )
• mice exhibit no obvious defects

skeleton
skeleton phenotype ( J:137385 )
N
• mice exhibit a normal vertebral column




Genotype
MGI:3801319
ht2
Allelic
Composition		 Kat2atm1Roth/Kat2atm3.2Roth
Genetic
Background		 involves: 129/Sv * 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kat2atm1Roth mutation (0 available); any Kat2a mutation (40 available)
Kat2atm3.2Roth mutation (1 available); any Kat2a mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:132940 )
• mice exhibit no obvious defects




Genotype
MGI:5315468
cn3
Allelic
Composition		 Kat2atm3.1Roth/Kat2atm3.2Roth
Tg(Pcp2-cre)2Mpin/0
Genetic
Background		 involves: 129
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kat2atm3.1Roth mutation (1 available); any Kat2a mutation (40 available)
Kat2atm3.2Roth mutation (1 available); any Kat2a mutation (40 available)
Tg(Pcp2-cre)2Mpin mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
behavior/neurological phenotype ( J:179021 )
N
• mutants exhibit normal hind limb extension in tail suspensions assays
abnormal gait ( J:179021 )
• mutants develop a mildly uncoordinated gait with wider paired distance

nervous system
abnormal cerebellum vermis morphology ( J:179021 )
• the cerebellar vermis is smaller




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory