Phenotypes associated with this allele

• Allele Symbol: Cul7^tm1Zqp
• Allele Name: targeted mutation 1, Zhen-Qiang Pan
• Allele ID: MGI:3801047
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Cul7^tm1Zqp/Cul7^tm1Zqp	involves: 129S/SvEv * C57BL/6J	MGI:3801058

Genotype
MGI:3801058

hm1

• Allelic Composition: Cul7^tm1Zqp/Cul7^tm1Zqp
• Genetic Background: involves: 129S/SvEv * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

lethality throughout fetal growth and development, complete penetrance ( J:137062 )

• no homozygous offspring by heterozygous crosses were observed

• live homozygous embryos were identified at E14.5

growth/size/body

fetal growth retardation ( J:137062 )

• exhibited gross growth retardation at E14.5

cellular

early cellular replicative senescence ( J:137062 )

• in MEF isolated from E14.5 homozygous embryo