Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd207tm1(Hbegf/EGFP)Bjec mutation
(0 available);
any
Cd207 mutation
(25 available)
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immune system
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• contact hypersensitivity assessed by ear swelling is attenuated at 24 hours after hapten challenge (mice were treated with diptheria toxin to induce deletion of Cd207 postive dendritic cells)
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd207tm1(Hbegf/EGFP)Bjec mutation
(0 available);
any
Cd207 mutation
(25 available)
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immune system
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• following intratracheally treatment with diphtheria toxin, CD11b-CD11chi dendritic ccells are depleted in the lungs
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• following treatment with diphtheria toxin, mice exhibit a rapid and complete ablation of Langerhans cells and recovery does not occur for 4 weeks
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• following treatment with diphtheria toxin
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• following intratracheally administration of diphtheria toxin, mice exhibit increased severity of influenza infection, increased weight lose and delayed clearance compared to infected wild-type mice
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hematopoietic system
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• following intratracheally treatment with diphtheria toxin, CD11b-CD11chi dendritic ccells are depleted in the lungs
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• following treatment with diphtheria toxin, mice exhibit a rapid and complete ablation of Langerhans cells and recovery does not occur for 4 weeks
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Analysis Tools