Phenotypes associated with this allele

• Allele Symbol: Arid1a^tm1.2Zhwa
• Allele Name: targeted mutation 1.2, Zhong Wang
• Allele ID: MGI:3796520
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Arid1a^tm1.2Zhwa/Arid1a^tm1.2Zhwa	involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6	MGI:3796530

Genotype
MGI:3796530

hm1

• Allelic Composition: Arid1a^tm1.2Zhwa/Arid1a^tm1.2Zhwa
• Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality between implantation and somite formation, complete penetrance ( J:134633 )

• embryos fail to develop past E6.5

embryo

failure to gastrulate ( J:134633 )

• embryos fail to gastrulate

embryonic growth arrest ( J:134633 )

• embryos arrest growth at E6.5

absent mesoderm ( J:134633 )

• E6.5 embryos have primitive endoderm and epiblast cell layers but fail to form a mesoderm

abnormal pluripotent precursor cell morphology ( J:134633 )

• ES cells derived from E3.5 embryos differentiate into an endoderm-like cells similar in morphology and growth properties to extraembryonic endoderm cells