Analysis Tools|
Allele Symbol Allele Name Allele ID |
Mirc1+ wild type MGI:3796145 |
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| Summary |
12 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• the fifth mesophalanx of the forelimb is shortened, but phenotype is less than in homozygotes
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• the fifth mesophalanx of the forelimb is shortened, but phenotype is less than in homozygotes
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• 17% of mice exhibit vertebral fusion
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• 72% of mice exhibit fusion of the proximal carpal bones
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• the fifth mesophalanx of the forelimb is shortened in E18.5 embryos
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• 72% of mice exhibit fusion of the proximal carpal bones
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• the fifth mesophalanx of the forelimb is shortened in E18.5 embryos
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• 46% of mice exhibit transformation of vertebra 26 (L6 to S1)
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• the fifth mesophalanx of the forelimb is shortened, but the phenotype is less severe than in homozygotes
|
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• the fifth mesophalanx of the forelimb is shortened, but the phenotype is less severe than in homozygotes
|
|
|
| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
|
• the fifth mesophalanx of the forelimb is shortened, but phenotype is less severe than in homozygotes
|
|
• the fifth mesophalanx of the forelimb is shortened, but phenotype is less severe than in homozygotes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• the anterior-posterior axis of the skull is shortened and the skull shows an overall reduction in size
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• 4-5 week old mice weigh less than controls
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• mesophalanx of the fifth finger is shorter
• however, other long bones in the hands are only marginally shorter than in wild-type and syndactyly is not observed
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• mesophalanx of the fifth finger is shorter
• however, other long bones in the hands are only marginally shorter than in wild-type and syndactyly is not observed
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Mouse Models of Human Disease |
DO ID | OMIM ID(s) | Ref(s) | |
| Feingold syndrome | DOID:0060464 |
OMIM:164280 OMIM:614326 |
J:188762 | |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• newborn mice are slightly smaller than wild-type littermates
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• 4-5 week old mice weigh 16% less than controls, but more than homozygotes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/18/2025 MGI 6.24 |
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