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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Pik3catm3Bvan
targeted mutation 3, Bart Vanhaesebroeck
MGI:3795787
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
 		Pik3catm3Bvan/Pik3catm3Bvan
Tg(Tek-cre)1Ywa/0 		involves: 129P2/OlaHsd * C57BL/6 * SJL MGI:3796332


Genotype
MGI:3796332
cn1
Allelic
Composition		 Pik3catm3Bvan/Pik3catm3Bvan
Tg(Tek-cre)1Ywa/0
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * SJL
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pik3catm3Bvan mutation (1 available); any Pik3ca mutation (65 available)
Tg(Tek-cre)1Ywa mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

embryo
abnormal vitelline vascular remodeling ( J:136236 )
• by E10.5, mice exhibit a defective remodeling of the primary yolk sac plexus

cardiovascular system
abnormal vascular development ( J:136236 )
• at E10.5, mice develop vascular abnormalities similar to those observed in Pik3catm1Bvan homozygotes




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory