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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Gata1tm10Sho
targeted mutation 10, Stuart H Orkin
MGI:3778536
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
ot1
 		Gata1tm10Sho/Y involves: C57BL/6 MGI:3809765


Genotype
MGI:3809765
ot1
Allelic
Composition		 Gata1tm10Sho/Y
Genetic
Background		 involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gata1tm10Sho mutation (0 available); any Gata1 mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
hematopoietic system phenotype ( J:132560 )
N
• in adults peripheral blood parameters are not significantly different from wild-type littermates
• at E17.5 and E18.5 peripheral blood parameters are normal
decreased erythroid progenitor cell number ( J:132560 )
• decrease in both erythroid burst forming unit and erythroid colony forming unit progenitor populations in the bone marrow




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory