Phenotypes associated with this allele

• Allele Symbol: Atp7a^Mo-Btlr
• Allele Name: mottled Bruce Beutler
• Allele ID: MGI:3777914
• Summary: 2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Atp7a^Mo-Btlr/Atp7a^+	C57BL/6J-Atp7a^Mo-Btlr	MGI:3777915
ot2	Atp7a^Mo-Btlr/Y	C57BL/6J-Atp7a^Mo-Btlr	MGI:3777916

Genotype
MGI:3777915

ht1

• Allelic Composition: Atp7a^Mo-Btlr/Atp7a⁺
• Genetic Background: C57BL/6J-Atp7a^Mo-Btlr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Coat color phenotypes of mutants carrying the Atp7a^Mo-Btlr, Atp7a^Mo-2Btlr, or Atp7a^Mo-3Btlr allele

pigmentation

mosaic coat color ( J:133115 , J:188598 )

♀ • the dorsal, ventral and facial fur of female mice (and skin of neonatal females) heterozygous for the tigrou-like mutation appears black with brown stripes that seem not to cross the midline; the brown stripes lighten over time (J:133115)

♀ (J:188598)

integument

mosaic coat color ( J:133115 , J:188598 )

♀ • the dorsal, ventral and facial fur of female mice (and skin of neonatal females) heterozygous for the tigrou-like mutation appears black with brown stripes that seem not to cross the midline; the brown stripes lighten over time (J:133115)

♀ (J:188598)

Genotype
MGI:3777916

ot2

• Allelic Composition: Atp7a^Mo-Btlr/Y
• Genetic Background: C57BL/6J-Atp7a^Mo-Btlr

mortality/aging

perinatal lethality, complete penetrance ( J:133115 )

♂ • male mice hemizygous for this mutation die, most likely before but possibly at birth

prenatal lethality, complete penetrance ( J:188598 )

♂ • no males observed postpartum