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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Map3k12Gt(RRN366)Byg
gene trap RRN366, BayGenomics
MGI:3760641
Summary 3 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Map3k12Gt(RRN366)Byg/Map3k12Gt(RRN366)Byg involves: 129P2/OlaHsd * C57BL/6 MGI:3760659
hm2
Map3k12Gt(RRN366)Byg/Map3k12Gt(RRN366)Byg involves: 129P2/OlaHsd * C57BL/6J MGI:5440726
cx3
Map3k12Gt(RRN366)Byg/Map3k12Gt(RRN366)Byg
Mycbp2tm1.1Adia/Mycbp2tm1.1Adia
involves: 129P2/OlaHsd * C57BL/6 * FVB/N MGI:3760660


Genotype
MGI:3760659
hm1
Allelic
Composition
Map3k12Gt(RRN366)Byg/Map3k12Gt(RRN366)Byg
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map3k12Gt(RRN366)Byg mutation (1 available); any Map3k12 mutation (39 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• mice lack the anterior commissure
• however, the brain internal capsule is present




Genotype
MGI:5440726
hm2
Allelic
Composition
Map3k12Gt(RRN366)Byg/Map3k12Gt(RRN366)Byg
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map3k12Gt(RRN366)Byg mutation (1 available); any Map3k12 mutation (39 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• in vitro and in vivo

homeostasis/metabolism
• in vitro and in vivo




Genotype
MGI:3760660
cx3
Allelic
Composition
Map3k12Gt(RRN366)Byg/Map3k12Gt(RRN366)Byg
Mycbp2tm1.1Adia/Mycbp2tm1.1Adia
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map3k12Gt(RRN366)Byg mutation (1 available); any Map3k12 mutation (39 available)
Mycbp2tm1.1Adia mutation (0 available); any Mycbp2 mutation (223 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• authors state that mice exhibit the same gross morphological defects as observed in Phr1tm1.1Adia homozygotes
• lateral ventricles are increased in size
• mice lack the axon tract that runs through the internal capsule





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory