Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pepddal mutation
(1 available);
any
Pepd mutation
(37 available)
Tg(Myh6*/tetO-GCaMP2)1Mik mutation
(1 available)
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cardiovascular system
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• 43% of E12.5 dark-like homozygotes display abnormal calcium transients such as early after-depolarizations and interval irregularities, and those hearts that have these abnormalities also have thickened ventricular walls whereas those not displaying irregularities in calcium handling appeared normal
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Myh6*/tetO-GCaMP2)1Mik mutation
(1 available)
Tg(Myh6-tTA)55Rbns mutation
(2 available)
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cardiovascular system
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• cardiomegaly develops in adults in the absence of dox (unregulated expression of GCaMP2); double transgenics maintained on dox have normal heart size
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growth/size/body
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• cardiomegaly develops in adults in the absence of dox (unregulated expression of GCaMP2); double transgenics maintained on dox have normal heart size
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Analysis Tools