Analysis Tools
mortality/aging
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• heterozygous mating did not produce homozygous mice
• timing of lethality was not determined
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Allele Symbol Allele Name Allele ID |
Wt1tm1Nhsn targeted mutation 1, Naoki Hosen MGI:3721102 |
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| Summary |
3 genotypes
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• heterozygous mating did not produce homozygous mice
• timing of lethality was not determined
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• heterozygous mice are indistinguishable with respect to hematopoietic cellularity and lineage composition from wild-type littermates
• loss of a single allele did not affect viability and expected Mendelian ratio of heterozygous mice are born by heterozygous crosses
• used for expression study only
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| ♀ | phenotype observed in females |
| ♂ | phenotype observed in males |
| N | normal phenotype |
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• mice die between E16.5 and E18.5 as a result of cardiovascular failure
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• some mice exhibit thinner free walls compared to in wild-type mice
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• mice die between E16.5 and E18.5 as a result of cardiovascular failure
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• mice exhibit pericardial hemorrhaging unlike wild-type mice
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• at E16.5, mice exhibit an accumulation of blood in the systemic veins unlike in wild-type mice
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• mice exhibit pericardial hemorrhaging unlike wild-type mice
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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