About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hrktm1Ast
targeted mutation 1, Andreas Strasser
MGI:3720713
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hrktm1Ast/Hrktm1Ast C57BL/6-Hrktm1Ast MGI:3721271


Genotype
MGI:3721271
hm1
Allelic
Composition		 Hrktm1Ast/Hrktm1Ast
Genetic
Background		 C57BL/6-Hrktm1Ast
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased neuron apoptosis ( J:124044 )
• dorsal root ganglia sensory neurons are less sensitive than wild-type neurons to apoptosis induced by the withdrawal of nerve growth factor
abnormal dorsal root ganglion morphology ( J:124044 )
• dorsal root ganglia sensory neurons are less sensitive than wild-type neurons to apoptosis induced by the withdrawal of nerve growth factor

cellular
decreased neuron apoptosis ( J:124044 )
• dorsal root ganglia sensory neurons are less sensitive than wild-type neurons to apoptosis induced by the withdrawal of nerve growth factor




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory