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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Hrktm1Ast
targeted mutation 1, Andreas Strasser
MGI:3720713
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Hrktm1Ast/Hrktm1Ast C57BL/6-Hrktm1Ast MGI:3721271


Genotype
MGI:3721271
hm1
Allelic
Composition		 Hrktm1Ast/Hrktm1Ast
Genetic
Background		 C57BL/6-Hrktm1Ast
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
decreased neuron apoptosis ( J:124044 )
• dorsal root ganglia sensory neurons are less sensitive than wild-type neurons to apoptosis induced by the withdrawal of nerve growth factor
abnormal dorsal root ganglion morphology ( J:124044 )
• dorsal root ganglia sensory neurons are less sensitive than wild-type neurons to apoptosis induced by the withdrawal of nerve growth factor

cellular
decreased neuron apoptosis ( J:124044 )
• dorsal root ganglia sensory neurons are less sensitive than wild-type neurons to apoptosis induced by the withdrawal of nerve growth factor




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory