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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tg(Thy1-MAPT)5Vln
transgene insertion 5, Fred Van Leuven
MGI:3720115
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
cx1
Ppp2r5dtm1Vjan/Ppp2r5dtm1Vjan
Tg(Thy1-MAPT)5Vln/0
involves: 129P2/OlaHsd * C57BL/6 * FVB/N MGI:4950910
tg2
Tg(Thy1-MAPT)5Vln/Tg(Thy1-MAPT)5Vln involves: FVB MGI:3720207


Genotype
MGI:4950910
cx1
Allelic
Composition
Ppp2r5dtm1Vjan/Ppp2r5dtm1Vjan
Tg(Thy1-MAPT)5Vln/0
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppp2r5dtm1Vjan mutation (0 available); any Ppp2r5d mutation (33 available)
Tg(Thy1-MAPT)5Vln mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice take more time to remove an adhesive sticker than Tg(Thy1-MAPT)5Vln mice
• in beam walk and rotatrod tests to a greater extent than in either Ppp2r5dtm1Vjan homozygotes or Tg(Thy1-MAPT)5Vln mice
• compared with Tg(Thy1-MAPT)5Vln mice




Genotype
MGI:3720207
tg2
Allelic
Composition
Tg(Thy1-MAPT)5Vln/Tg(Thy1-MAPT)5Vln
Genetic
Background
involves: FVB
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• dilated axons are observed in brain and spinal cord

behavior/neurological
• compared to wild-type mice, mutants are 5 times more likely to fall off of a rotating rod in a rotarod test





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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory