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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Fmn1ld-Lsk
limb deformity, Lawrence S Kirschner
MGI:3718051
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Fmn1ld-Lsk/Fmn1ld-Lsk C.Cg-Fmn1ld-Lsk MGI:3718378


Genotype
MGI:3718378
hm1
Allelic
Composition
Fmn1ld-Lsk/Fmn1ld-Lsk
Genetic
Background
C.Cg-Fmn1ld-Lsk
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fmn1ld-Lsk mutation (0 available); any Fmn1 mutation (75 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• at P14, mice exhibit various distal limb and paw defects
• at 6 months, mice exhibit upper limb defects and fail to develop distal paw structures
• defects are first visible at E12.5
• at 6 months, mice fail to develop distal paw structures and instead possess three rudimentary digit structures
• paws are malrotated
• mice lack the calcaneus
• at 6 month, mice have fused radius and ulna
• at 6 month, mice have fused radius and ulna

skeleton
• mice lack the calcaneus
• at 6 month, mice have fused radius and ulna
• at 6 month, mice have fused radius and ulna





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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory