Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itga2btm1Graf mutation
(0 available);
any
Itga2b mutation
(45 available)
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|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itga2btm1Graf mutation
(0 available);
any
Itga2b mutation
(45 available)
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hematopoietic system
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• following whole body irradiation, the numbe rof YFP+ platelets decreases by 2-fold after day 6 of exposure
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• YFP+ platelets are more responsive to thrombin stimulation than YFP- platelets within the same mouse
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homeostasis/metabolism
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itga2btm1Graf mutation
(0 available);
any
Itga2b mutation
(45 available)
Tfpitm1Gjb mutation
(0 available);
any
Tfpi mutation
(45 available)
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mortality/aging
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• 3 of 6 mice die by 4 weeks of age
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• incomplete rescue of pre-weaning lethality
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nervous system
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• in mice that die by 4 weeks of age
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• compared with mice heterozygous for a Tfpi null allele
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skeleton
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• in mice that die by 4 weeks of age
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craniofacial
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• in mice that die by 4 weeks of age
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