Itga2b^tm1Graf
Targeted Allele Detail

Summary

• Symbol: Itga2b^tm1Graf
• Name: integrin alpha 2b; targeted mutation 1, Thomas Graf
• MGI ID: MGI:3717592
• Synonyms: CD41-YFP^ki, CD41:YFPtg
• Gene: Itga2b Location: Chr11:102344123-102360709 bp, - strand Genetic Position: Chr11, 66.29 cM
• Alliance: Itga2b^tm1Graf page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:123159
• Parent Cell Line: WW6 (ES Cell)
• Strain of Origin: STOCK 129/Sv and C57BL/6J and SJL

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A YFP gene was inserted right after the endogenous promoter. A floxed neo was included in the vector. (J:123159)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Itga2b Mutation: 45 strains or lines available

References

• Original: J:123159 Zhang J, et al., CD41-YFP mice allow in vivo labeling of megakaryocytic cells and reveal a subset of platelets hyperreactive to thrombin stimulation. Exp Hematol. 2007 Mar;35(3):490-499
• All: 17 reference(s)