Phenotypes associated with this allele

• Allele Symbol: Or51e2^tm1Jgst
• Allele Name: targeted mutation 1, Jorg Strotmann
• Allele ID: MGI:3712895
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Lhx2^tm1Dra/Lhx2^tm1Dra Or51e2^tm1Jgst/Or51e2^+	involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ	MGI:3718037

Genotype
MGI:3718037

cx1

• Allelic Composition: Lhx2^tm1Dra/Lhx2^tm1Dra; Or51e2^tm1Jgst/Or51e2⁺
• Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal olfactory sensory neuron morphology ( J:123232 )

• at E16.5, fewer and shorter axons from olfactory sensory neurons extend to the olfactory bulb

• however, Ilfr78+ olfactory sensory neurons differentiate normally

abnormal olfactory bulb morphology ( J:123232 )

• mice lack a well developed olfactory bulb due to gross brain malformation

• expression of ventral class I and all class II olfactory genes is lost

craniofacial

abnormal olfactory sensory neuron morphology ( J:123232 )

• at E16.5, fewer and shorter axons from olfactory sensory neurons extend to the olfactory bulb

• however, Ilfr78+ olfactory sensory neurons differentiate normally

respiratory system

abnormal olfactory sensory neuron morphology ( J:123232 )

• at E16.5, fewer and shorter axons from olfactory sensory neurons extend to the olfactory bulb

• however, Ilfr78+ olfactory sensory neurons differentiate normally

taste/olfaction

abnormal olfactory sensory neuron morphology ( J:123232 )

• at E16.5, fewer and shorter axons from olfactory sensory neurons extend to the olfactory bulb

• however, Ilfr78+ olfactory sensory neurons differentiate normally

growth/size/body

abnormal olfactory sensory neuron morphology ( J:123232 )

• at E16.5, fewer and shorter axons from olfactory sensory neurons extend to the olfactory bulb

• however, Ilfr78+ olfactory sensory neurons differentiate normally