Phenotypes associated with this allele
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hdac2Gt(W035F03)Joe mutation
(0 available);
any
Hdac2 mutation
(38 available)
Tg(Myh6-Hod)3Joe mutation
(0 available)
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cardiovascular system
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• at 4 weeks, mice have an increased heart to body weight ratios
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• at 8 weeks, mice exhibit increasing cardiac hypertrophy
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growth/size/body
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• at 4 weeks, mice have an increased heart to body weight ratios
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• at 8 weeks, mice exhibit increasing cardiac hypertrophy
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| Find Mice |
Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
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mortality/aging
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• mean survival is 32 weeks
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cardiovascular system
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• heart to body weight ratio is increased about 25%
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• mice exhibit increasing cardiac hypertrophy
(J:121677)
• as early a 3 weeks after birth
(J:121995)
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• severe concentric left and right ventricular hypertrophy that progressed variably to cardiac dilatation accompanied by heart failure
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• 5+/-1mmHg compared to 2+/-0.3mmHg in wild-type mice
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• impaired diastolic relaxation with no change in systolic blood pressure
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• some mice experience heart failure
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muscle
growth/size/body
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• heart to body weight ratio is increased about 25%
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• mice exhibit increasing cardiac hypertrophy
(J:121677)
• as early a 3 weeks after birth
(J:121995)
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Analysis Tools