Hdac2Gt(W035F03)Joe
Gene trapped Allele Detail
|
Symbol: |
Hdac2Gt(W035F03)Joe |
Name: |
histone deacetylase 2; gene trap W035F03, Jonathan A Epstein |
MGI ID: |
MGI:3712002 |
Synonyms: |
Hdac2- |
Gene: |
Hdac2 Location: Chr10:36850540-36877885 bp, + strand Genetic Position: Chr10, 19.44 cM, cytoband B1
|
Alliance: |
Hdac2Gt(W035F03)Joe page
|
|
Mutant Cell Line: |
W035F03 |
Germline Transmission: |
Earliest citation of germline transmission:
J:121697
|
Parent Cell Line: |
TBV2 (ES Cell)
|
Strain of Origin: |
129S2/SvPas
|
|
Allele Type: |
|
Gene trapped (Null/knockout, Reporter) |
Mutation: |
|
Insertion of gene trap vector
Vector: pT1betageo
|
|
|
Mutation details: A gene trap containing lacZ was inserted into intron 8 and removed exons 9-14, which encode portions of the catalyitic domain. Western blot demonstrated absence of protein from mutant embryos.
(J:121697)
|
Sequence Tags: |
|
Sequence tag details (1 tag)
Tag ID |
GenBank ID |
Method |
Tag Location (trapped strand)* |
Select |
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Hdac2 Mutation: |
38 strains or lines available
|
|
Original: |
J:121697 Trivedi CM, et al., Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity. Nat Med. 2007 Mar;13(3):324-31 |
All: |
7 reference(s) |
|