Phenotypes associated with this allele

• Allele Symbol: Card10^tm1Xlin
• Allele Name: targeted mutation 1, Xin Lin
• Allele ID: MGI:3710003
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Card10^tm1Xlin/Card10^tm1Xlin	involves: 129/Sv * C57BL/6	MGI:3711132

Genotype
MGI:3711132

hm1

• Allelic Composition: Card10^tm1Xlin/Card10^tm1Xlin
• Genetic Background: involves: 129/Sv * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

perinatal lethality, incomplete penetrance ( J:121114 )

• increase in perinatal mortality from 50% of mice with anencephaly due to bleed out from the skull or infanticide by the mother

nervous system

anencephaly ( J:121114 )

• anencephaly is observed in E10.5 embryos and in 50% of mice at E13.5

• however, the remaining 50% of mice have no neural tube defects and grow normally