Phenotypes associated with this allele

• Allele Symbol: Loxhd1^sba
• Allele Name: samba
• Allele ID: MGI:3708447
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Loxhd1^sba/Loxhd1^sba	involves: C57BL/6J	MGI:3709046

Genotype
MGI:3709046

hm1

• Allelic Composition: Loxhd1^sba/Loxhd1^sba
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hearing/vestibular/ear

abnormal cochlear hair cell morphology ( J:154318 )

• by P21, some hair cells in the basal turn of the cochlea exhibit fused stereocilia and membrane ruffling at the apical cell surface unlike in wild-type mice

cochlear hair cell degeneration ( J:154318 )

• profound by P90

abnormal auditory brainstem response ( J:154318 )

• by 3 weeks of age

increased or absent threshold for auditory brainstem response ( J:119820 )

• auditory threshold of more than 90 dB, indicating that lines are severely hearing impaired in 8- to 12-weeks old animals

absent distortion product otoacoustic emissions ( J:154318 )

• at 3 weeks of age

nervous system

abnormal cochlear hair cell morphology ( J:154318 )

• by P21, some hair cells in the basal turn of the cochlea exhibit fused stereocilia and membrane ruffling at the apical cell surface unlike in wild-type mice

cochlear hair cell degeneration ( J:154318 )

• profound by P90

cochlear ganglion degeneration ( J:154318 )

• profound by P90

behavior/neurological

decreased startle reflex ( J:119820 )

• low auditory startle response