Phenotypes associated with this allele

• Allele Symbol: Myo6^twt
• Allele Name: twist
• Allele ID: MGI:3708361
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Myo6^twt/Myo6^twt	involves: C57BL/6J	MGI:3709035

Genotype
MGI:3709035

hm1

• Allelic Composition: Myo6^twt/Myo6^twt
• Genetic Background: involves: C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

decreased startle reflex ( J:119820 )

• low auditory startle response

impaired swimming ( J:119820 )

• disoriented

hyperactivity ( J:119820 )

circling ( J:119820 )

hearing/vestibular/ear

abnormal cochlear hair cell stereociliary bundle morphology ( J:119820 )

• hair bundles are disorganized, fragmented, and frequently contain malformed stereocilia in reduced numbers

decreased cochlear hair cell stereocilia number ( J:119820 )

increased or absent threshold for auditory brainstem response ( J:119820 )

• auditory threshold of more than 90 dB, indicating that lines are severely hearing impaired in 3-week-old and 2-month-old animals

nervous system

abnormal cochlear hair cell stereociliary bundle morphology ( J:119820 )

• hair bundles are disorganized, fragmented, and frequently contain malformed stereocilia in reduced numbers

decreased cochlear hair cell stereocilia number ( J:119820 )