All Phenotypes Unc79<Lwt> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Unc79^Lwt
lightweight
MGI:3701691

Summary

4 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Unc79^Lwt/Unc79^Lwt	B6.D2-Unc79^Lwt	MGI:4822556
hm2	Unc79^Lwt/Unc79^Lwt	involves: C57BL/6J * DBA/2J	MGI:3702108
ht3	Unc79^Lwt/Unc79⁺	B6.D2-Unc79^Lwt	MGI:4822557
ht4	Unc79^Lwt/Unc79⁺	involves: C57BL/6J * DBA/2J	MGI:3702109

Allelic Composition	Unc79^Lwt/Unc79^Lwt
Genetic Background	B6.D2-Unc79^Lwt

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Unc79^Lwt mutation (0 available); any Unc79 mutation (126 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

perinatal lethality ( J:163308 )

Allelic Composition	Unc79^Lwt/Unc79^Lwt
Genetic Background	involves: C57BL/6J * DBA/2J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Unc79^Lwt mutation (0 available); any Unc79 mutation (126 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

increased locomotor activity ( J:118059 )

• increased spontaneous locomotor activity

Allelic Composition	Unc79^Lwt/Unc79⁺
Genetic Background	B6.D2-Unc79^Lwt

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Unc79^Lwt mutation (0 available); any Unc79 mutation (126 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

alcohol preference ( J:163308 )

• a higher preference for ethanol

enhanced behavioral response to alcohol ( J:163308 )

• an increase in sensitivity to the acute sedative effects of ethanol, loss of righting reflex test

impaired behavioral response to anesthetic ( J:163308 )

• resistance to isoflurane-induced anesthesia relative to wild-type littermates

increased fluid intake ( J:163308 )

• an increase in fluid consumption

increased alcohol consumption ( J:163308 )

• mice consume more ethanol

abnormal saccharin consumption ( J:163308 )

• an increase in the consumption of saccharin relative to wild-type

saccharin preference ( J:163308 )

• an increase in saccharin preference

hyperactivity ( J:163308 )

• modestly hyperactive

growth/size/body

decreased body weight ( J:163308 )

• weigh less than the wild-type

decreased body length ( J:163308 )

• mice are shorter in length

adipose tissue

decreased total body fat amount ( J:163308 )

• accumulate less fat

Allelic Composition	Unc79^Lwt/Unc79⁺
Genetic Background	involves: C57BL/6J * DBA/2J

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Unc79^Lwt mutation (0 available); any Unc79 mutation (126 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

increased locomotor activity ( J:118059 )

• increased spontaneous locomotor activity

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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