About   Help   FAQ
Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Ptcratm1(icre)Hjf
targeted mutation 1, Hans Jorg Fehling
MGI:3696089
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Ptcratm1(icre)Hjf/Ptcratm1(icre)Hjf B6.129P2-Ptcratm1(icre)Hjf MGI:5505821


Genotype
MGI:5505821
hm1
Allelic
Composition		 Ptcratm1(icre)Hjf/Ptcratm1(icre)Hjf
Genetic
Background		 B6.129P2-Ptcratm1(icre)Hjf
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptcratm1(icre)Hjf mutation (2 available); any Ptcra mutation (12 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased thymocyte number ( J:197923 )
• numbers are significantly decreased compared to controls
decreased DN4 thymocyte number ( J:197923 )
• phenotype is similar to that reported for Ptrca-null mice
decreased double-positive T cell number ( J:197923 )
• phenotype is similar to that reported for Ptrca-null mice

hematopoietic system
decreased thymocyte number ( J:197923 )
• numbers are significantly decreased compared to controls
decreased DN4 thymocyte number ( J:197923 )
• phenotype is similar to that reported for Ptrca-null mice
decreased double-positive T cell number ( J:197923 )
• phenotype is similar to that reported for Ptrca-null mice

endocrine/exocrine glands
decreased thymocyte number ( J:197923 )
• numbers are significantly decreased compared to controls
decreased DN4 thymocyte number ( J:197923 )
• phenotype is similar to that reported for Ptrca-null mice




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory