All Phenotypes Ptpn11<tm1Yan> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Ptpn11^tm1Yan
targeted mutation 1, Wentian Yang
MGI:3690333

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cn1	Ptpn11^tm1Yan/Ptpn11^tm1Yan Tg(Ckmm-cre)5Khn/0	involves: 129/Sv * C57BL/6 * FVB	MGI:3697622

Allelic Composition	Ptpn11^tm1Yan/Ptpn11^tm1Yan Tg(Ckmm-cre)5Khn/0
Genetic Background	involves: 129/Sv * C57BL/6 * FVB

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptpn11^tm1Yan mutation (1 available); any Ptpn11 mutation (43 available)
Tg(Ckmm-cre)5Khn mutation (4 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

muscle

decreased skeletal muscle fiber size ( J:114499 )

• exhibit a decrease in skeletal myofiber size concomitant with a reduction in larger myofibers as well as a decrease in myonuclear number

decreased skeletal muscle fiber number ( J:114499 )

• exhibit a decrease in the number of skeletal muscle fibers, more specifically a reduction in type I slow muscle fibers

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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