Phenotypes associated with this allele

• Allele Symbol: Fbxl3^Afh
• Allele Name: after hours
• Allele ID: MGI:3687377
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Fbxl3^Afh/Fbxl3^Afh	involves: BALB/c * C3H/HeH	MGI:3711662
ht2	Fbxl3^Afh/Fbxl3^+	involves: BALB/c * C3H/HeH	MGI:3711663
ht3	Fbxl3^Afh/Fbxl3^+	involves: BALB/cOlaHsd * C3H/HeH	MGI:3608425

Genotype
MGI:3711662

hm1

• Allelic Composition: Fbxl3^Afh/Fbxl3^Afh
• Genetic Background: involves: BALB/c * C3H/HeH

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

prolonged circadian behavior period ( J:121578 )

• period is very significantly lengthened (by ~3 hours) compared to wild-type, assessed by activity like wheel-running

nervous system

abnormal hypothalamus physiology ( J:121578 )

• suprachiasmatic nucleus molecular cycle period is lengthened in vitro

Genotype
MGI:3711663

ht2

• Allelic Composition: Fbxl3^Afh/Fbxl3⁺
• Genetic Background: involves: BALB/c * C3H/HeH

behavior/neurological

prolonged circadian behavior period ( J:121578 )

• period is very significantly lengthened (by ~0.5-1 hour) compared to wild-type, assessed by activity like wheel-running

nervous system

abnormal hypothalamus physiology ( J:121578 )

• suprachiasmatic nucleus molecular cycle period is lengthened in vitro

Genotype
MGI:3608425

ht3

• Allelic Composition: Fbxl3^Afh/Fbxl3⁺
• Genetic Background: involves: BALB/cOlaHsd * C3H/HeH

behavior/neurological

prolonged circadian behavior period ( J:101896 )

• the circadian period is 24.2 hours compared to 23.59 hours in wild-type mice