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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Tasp1tm1Jjdh
targeted mutation 1, James JD Hsieh
MGI:3687251
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cn1
Tasp1tm1Jjdh/Tasp1tm1Jjdh
Tg(Mx1-cre)1Cgn/?
involves: 129X1/SvJ * C57BL/6 * CBA MGI:3687261


Genotype
MGI:3687261
cn1
Allelic
Composition
Tasp1tm1Jjdh/Tasp1tm1Jjdh
Tg(Mx1-cre)1Cgn/?
Genetic
Background
involves: 129X1/SvJ * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tasp1tm1Jjdh mutation (0 available); any Tasp1 mutation (38 available)
Tg(Mx1-cre)1Cgn mutation (7 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• 50% reduction in thymus weight
• 54% reduction in total thymocyte number
• although double negative T cell numbers are normal, double positive T cell numbers are reduced about 60%

hematopoietic system
• 50% reduction in thymus weight
• 54% reduction in total thymocyte number
• although double negative T cell numbers are normal, double positive T cell numbers are reduced about 60%

endocrine/exocrine glands
• 50% reduction in thymus weight
• 54% reduction in total thymocyte number





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory