Phenotypes associated with this allele
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lfngtm1Rjo mutation
(0 available);
any
Lfng mutation
(32 available)
Mfngtm1Seco mutation
(1 available);
any
Mfng mutation
(33 available)
Rfngtm1Tfv mutation
(0 available);
any
Rfng mutation
(15 available)
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mortality/aging
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• fewer than expected are found at weaning however survivors are viable and fertile
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• fewer than expected are found at weaning
• reduction in numbers found at weaning is not greater than that of Lfngtm1Rjo single homozygous littermates
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skeleton
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• skeleton phenotype is not significantly different from that of Lfngtm1Rjo single homozygous mice
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limbs/digits/tail
N |
• unlike in chick embryo experiments, no limb abnormalities are seen
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Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
En1tm1Alj mutation
(2 available);
any
En1 mutation
(32 available)
Rfngtm1Tfv mutation
(0 available);
any
Rfng mutation
(15 available)
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limbs/digits/tail
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• at E10.5 the AER appears flattened and ventrally expanded
• by E11.5, clefts and bifurcations are seen along with ventral anterior nubs
• 2 distinct ectodermal ridges are present
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embryo
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• at E10.5 the AER appears flattened and ventrally expanded
• by E11.5, clefts and bifurcations are seen along with ventral anterior nubs
• 2 distinct ectodermal ridges are present
|
|
Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
En1tm1Alj mutation
(2 available);
any
En1 mutation
(32 available)
Rfngtm1Tfv mutation
(0 available);
any
Rfng mutation
(15 available)
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limbs/digits/tail
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• indistinguishable from mice with one wild-type Rfng allele at all stages examined
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• at E10.5 the AER appears flattened and ventrally expanded
• by E11.5, clefts and bifurcations are seen along with ventral anterior nubs
• 2 distinct ectodermal ridges are present
|
embryo
|
• at E10.5 the AER appears flattened and ventrally expanded
• by E11.5, clefts and bifurcations are seen along with ventral anterior nubs
• 2 distinct ectodermal ridges are present
|