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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Foxn1tm2Tbo
targeted mutation 2, Thomas Boehm
MGI:3653425
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Foxn1tm2Tbo/Foxn1tm2Tbo involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3653833
cn2
 		Foxn1tm2Tbo/Foxn1tm2Tbo
Tg(KRT14-cre/ERT2)1Ipc/0 		involves: 129S1/Sv * 129X1/SvJ * C57BL/6 MGI:3653834


Genotype
MGI:3653833
hm1
Allelic
Composition		 Foxn1tm2Tbo/Foxn1tm2Tbo
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxn1tm2Tbo mutation (0 available); any Foxn1 mutation (106 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
integument
hairless ( J:110046 )
• homozygotes lack a normal hair coat similar to nude (nu/nu) mice




Genotype
MGI:3653834
cn2
Allelic
Composition		 Foxn1tm2Tbo/Foxn1tm2Tbo
Tg(KRT14-cre/ERT2)1Ipc/0
Genetic
Background		 involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxn1tm2Tbo mutation (0 available); any Foxn1 mutation (106 available)
Tg(KRT14-cre/ERT2)1Ipc mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
increased T cell number ( J:110046 )
• mutants have higher proportions of activated peripheral T cells (CD44high CD62Llow CD25high) than wild-type

immune system
increased T cell number ( J:110046 )
• mutants have higher proportions of activated peripheral T cells (CD44high CD62Llow CD25high) than wild-type




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory