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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Il3ram1
mutation 1
MGI:3652833
Summary 10 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Il3ram1/Il3ram1 A/HeJ MGI:3837357
hm2
 		Il3ram1/Il3ram1 A/J MGI:3653035
hm3
 		Il3ram1/Il3ram1 AKR/J MGI:3837353
hm4
 		Il3ram1/Il3ram1 A/WySnJ MGI:3837356
hm5
 		Il3ram1/Il3ram1 BUB/BnJ MGI:3837358
hm6
 		Il3ram1/Il3ram1 C58/J MGI:3837352
hm7
 		Il3ram1/Il3ram1 CE/J MGI:3837360
hm8
 		Il3ram1/Il3ram1 NZB/BlNJ MGI:3837355
hm9
 		Il3ram1/Il3ram1 RF/J MGI:3837354
hm10
 		Il3ram1/Il3ram1 SM/J MGI:3837359


Genotype
MGI:3837357
hm1
Allelic
Composition		 Il3ram1/Il3ram1
Genetic
Background		 A/HeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il3ram1 mutation (12 available); any Il3ra mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal common myeloid progenitor cell morphology ( J:24918 )
• CFU-GM assays using bone marrow derived cells yield very few colonies in repsonse to interleukin 3




Genotype
MGI:3653035
hm2
Allelic
Composition		 Il3ram1/Il3ram1
Genetic
Background		 A/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il3ram1 mutation (12 available); any Il3ra mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal common myeloid progenitor cell morphology ( J:24918 )
• CFU-GM assays using bone marrow derived cells yield very few colonies in repsonse to interleukin 3, but normal colony growth occurs in response to GM-CSF
abnormal leukopoiesis ( J:23971 )
• Il3 alone does not support granulocyte/macrophage colony formation in bone marrow cells from A/J mice but does in bone marrow from C57BL/6 controls; costimulation with both Il3 and SCF increases the number of colonies formed compared to SCF alone

immune system
abnormal leukopoiesis ( J:23971 )
• Il3 alone does not support granulocyte/macrophage colony formation in bone marrow cells from A/J mice but does in bone marrow from C57BL/6 controls; costimulation with both Il3 and SCF increases the number of colonies formed compared to SCF alone




Genotype
MGI:3837353
hm3
Allelic
Composition		 Il3ram1/Il3ram1
Genetic
Background		 AKR/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il3ram1 mutation (12 available); any Il3ra mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal common myeloid progenitor cell morphology ( J:24918 )
• CFU-GM assays using bone marrow derived cells yield very few colonies in repsonse to interleukin 3




Genotype
MGI:3837356
hm4
Allelic
Composition		 Il3ram1/Il3ram1
Genetic
Background		 A/WySnJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il3ram1 mutation (12 available); any Il3ra mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal common myeloid progenitor cell morphology ( J:24918 )
• CFU-GM assays using bone marrow derived cells yield very few colonies in repsonse to interleukin 3




Genotype
MGI:3837358
hm5
Allelic
Composition		 Il3ram1/Il3ram1
Genetic
Background		 BUB/BnJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il3ram1 mutation (12 available); any Il3ra mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal common myeloid progenitor cell morphology ( J:24918 )
• CFU-GM assays using bone marrow derived cells yield very few colonies in repsonse to interleukin 3




Genotype
MGI:3837352
hm6
Allelic
Composition		 Il3ram1/Il3ram1
Genetic
Background		 C58/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il3ram1 mutation (12 available); any Il3ra mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal common myeloid progenitor cell morphology ( J:24918 )
• CFU-GM assays using bone marrow derived cells yield very few colonies in repsonse to interleukin 3




Genotype
MGI:3837360
hm7
Allelic
Composition		 Il3ram1/Il3ram1
Genetic
Background		 CE/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il3ram1 mutation (12 available); any Il3ra mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal common myeloid progenitor cell morphology ( J:24918 )
• CFU-GM assays using bone marrow derived cells yield very few colonies in repsonse to interleukin 3




Genotype
MGI:3837355
hm8
Allelic
Composition		 Il3ram1/Il3ram1
Genetic
Background		 NZB/BlNJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il3ram1 mutation (12 available); any Il3ra mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal common myeloid progenitor cell morphology ( J:24918 )
• CFU-GM assays using bone marrow derived cells yield very few colonies in repsonse to interleukin 3




Genotype
MGI:3837354
hm9
Allelic
Composition		 Il3ram1/Il3ram1
Genetic
Background		 RF/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il3ram1 mutation (12 available); any Il3ra mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal common myeloid progenitor cell morphology ( J:24918 )
• CFU-GM assays using bone marrow derived cells yield very few colonies in repsonse to interleukin 3




Genotype
MGI:3837359
hm10
Allelic
Composition		 Il3ram1/Il3ram1
Genetic
Background		 SM/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Il3ram1 mutation (12 available); any Il3ra mutation (36 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
abnormal common myeloid progenitor cell morphology ( J:24918 )
• CFU-GM assays using bone marrow derived cells yield very few colonies in repsonse to interleukin 3




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory