Analysis Tools
immune system
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• 24 hours after intraperitoneal injection of thioglycollate a delay in monocyte/macrophage early accumulation is seen; however, monocyte/macrophage numbers are similar to wild-type by 48 hours
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• mild monocytopenia in the peripheral blood; however hematopoiesis in the bone marrow is similar to wild-type
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• intraperitoneal injection of thioglycollate results in negligible recruitment of lymphocytes into the peritoneum over a 72 hour-period after injection; however neutrophil recruitment is similar to wild-type
• in adoptive transfer experiments homing of lymphoctes to secondary lymphoid tissues is similar to wild-type but recruitment to an inflamed peritoneal cavity is impaired
• however; humoral immune responses are similar to wild-type
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• numbers of B2, but not B1, cells are decreased in the peritoneum after intraperitoneal injection of thioglycollate compared to wild-type mice
• the decrease in accumulation of B cells in the inflamed peritoneum is more pronounced than for T cells although both are decreased
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• the decrease in accumulation of B cells in the inflamed peritoneum is more pronounced than for T cells although both are decreased
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• fewer Peyer's patches are seen in the gut; however those present have normal morphology and proportions of T and B cells
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hematopoietic system
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• 24 hours after intraperitoneal injection of thioglycollate a delay in monocyte/macrophage early accumulation is seen; however, monocyte/macrophage numbers are similar to wild-type by 48 hours
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• mild monocytopenia in the peripheral blood; however hematopoiesis in the bone marrow is similar to wild-type
|
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• intraperitoneal injection of thioglycollate results in negligible recruitment of lymphocytes into the peritoneum over a 72 hour-period after injection; however neutrophil recruitment is similar to wild-type
• in adoptive transfer experiments homing of lymphoctes to secondary lymphoid tissues is similar to wild-type but recruitment to an inflamed peritoneal cavity is impaired
• however; humoral immune responses are similar to wild-type
|
|
• numbers of B2, but not B1, cells are decreased in the peritoneum after intraperitoneal injection of thioglycollate compared to wild-type mice
• the decrease in accumulation of B cells in the inflamed peritoneum is more pronounced than for T cells although both are decreased
|
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• the decrease in accumulation of B cells in the inflamed peritoneum is more pronounced than for T cells although both are decreased
|
cellular
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• 24 hours after intraperitoneal injection of thioglycollate a delay in monocyte/macrophage early accumulation is seen; however, monocyte/macrophage numbers are similar to wild-type by 48 hours
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