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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Arhgef4+
wild type
MGI:3613539
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
cx1
 		ApcMin/Apc+
Arhgef4tm1Taki/Arhgef4+ 		B6J.Cg-Arhgef4tm1Taki ApcMin MGI:5881920


Genotype
MGI:5881920
cx1
Allelic
Composition		 ApcMin/Apc+
Arhgef4tm1Taki/Arhgef4+
Genetic
Background		 B6J.Cg-Arhgef4tm1Taki ApcMin
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
ApcMin mutation (12 available); any Apc mutation (151 available)
Arhgef4tm1Taki mutation (0 available); any Arhgef4 mutation (74 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
decreased intestinal adenoma incidence ( J:157023 )
• at 4 months of age, mice show an intermediate reduction in the total number of intestinal adenomas (polyps) per mouse relative to mice that are homozygous for Arhgef4tm1Taki and heterozygous for ApcMin
decreased tumor growth/size ( J:157023 )
• at 4 months of age, mice show an intermediate reduction in the size of intestinal adenomas (polyps) relative to mice that are homozygous for Arhgef4tm1Taki and heterozygous for ApcMin

digestive/alimentary system
decreased intestinal adenoma incidence ( J:157023 )
• at 4 months of age, mice show an intermediate reduction in the total number of intestinal adenomas (polyps) per mouse relative to mice that are homozygous for Arhgef4tm1Taki and heterozygous for ApcMin




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
12/30/2025
MGI 6.24 		The Jackson Laboratory