Phenotypes associated with this allele

• Allele Symbol: Trpm5^tm1Sdmk
• Allele Name: targeted mutation 1, Sami Damak
• Allele ID: MGI:3612408
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Trpm5^tm1Sdmk/Trpm5^tm1Sdmk	involves: C57BL/6	MGI:3615507

Genotype
MGI:3615507

hm1

• Allelic Composition: Trpm5^tm1Sdmk/Trpm5^tm1Sdmk
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

taste/olfaction

abnormal taste sensitivity ( J:103852 )

abnormal bitter taste sensitivity ( J:103852 )

• chorda tympani nerve responses to bitter compounds similar to response to sweet compounds

abnormal salty taste sensitivity ( J:103852 )

• chorda tympani nerve responses to salt similar to response to sweet compounds

abnormal sour taste sensitivity ( J:103852 )

• chorda tympani nerve responses to acid compounds similar to response to sweet compounds

abnormal sweet taste sensitivity ( J:103852 )

• chorda tympani nerve response to sweet compounds applied to the anterior taste field of the tongue is greatly reduced but not eliminated

• no enhancement of response to sweet compounds by increased temperature

abnormal umami taste sensitivity ( J:103852 , J:104626 )

• chorda tympani nerve responses to monosodium glutamate similar to response to sweet compounds (J:103852)

• residual responses to 100 and 300 mM monosodium glutamate in a two bottle preference test (J:104626)