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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Apba1tm1Amor
targeted mutation 1, Atsushi Mori
MGI:3609568
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Apba1tm1Amor/Apba1tm1Amor involves: 129 * C57BL/6J MGI:3611777


Genotype
MGI:3611777
hm1
Allelic
Composition		 Apba1tm1Amor/Apba1tm1Amor
Genetic
Background		 involves: 129 * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Apba1tm1Amor mutation (1 available); any Apba1 mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal behavior ( J:102794 )
• showed more sensitive and prominent behavioral response to an approaching object
impaired behavioral response to addictive substance ( J:102794 )
• methamphetamine induced stereotypy was significantly attenuated

homeostasis/metabolism
abnormal dopamine level ( J:102794 )
• the neurotransmitter dopamine release in mutant mice was suppressed only when the release was stimulated by a high potassium or methamphetamine




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory