About   Help   FAQ
Apba1tm1Amor
Targeted Allele Detail
Summary
Symbol: Apba1tm1Amor
Name: amyloid beta precursor protein binding family A member 1; targeted mutation 1, Atsushi Mori
MGI ID: MGI:3609568
Gene: Apba1  Location: Chr19:23736251-23926960 bp, + strand  Genetic Position: Chr19, 18.45 cM
Alliance: Apba1tm1Amor page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:102794
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129S/Sv
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 1.0-kb sequence containing the first methionine of the gene was replaced with the pMC1-neomycin-polyA cassette. Northern and Western blot analyses failed to detect transcript and protein, respectively, in mutant brain samples. (J:102794)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Apba1 Mutation:  32 strains or lines available
Notes
ES cell line = CCE28
References
Original:  J:102794 Mori A, et al., Alteration of methamphetamine-induced striatal dopamine release in mint-1 knockout mice. Neurosci Res. 2002 Jul;43(3):251-7
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
09/24/2024
MGI 6.24
The Jackson Laboratory