Phenotypes associated with this allele
|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Xcr1tm1Dgen mutation
(1 available);
any
Xcr1 mutation
(32 available)
|
|
|
immune system
|
N |
• mice exhibit normal immune cell composition
|
|
|
• CD8+ dendritic cells fail to migrate in response to XCL1 unlike similarly treated wild-type cells
|
|
|
| Find Mice |
Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Xcr1tm1Dgen mutation
(1 available);
any
Xcr1 mutation
(32 available)
|
|
|
normal phenotype
|
|
• no significant differences in physical examinations, necropsy including body length, body weight, and organ weight measurements, histological examination of tissues and organs, bone marrow section evaluations, complete blood counts and differentials, clinical chemistry panels, densitometry, behavior tests, fertility, or aging studies detected in the homozygous mutant mice when compared with age- and gender-matched wild-type control mice
|
Analysis Tools