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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
B3galt2tm1Dgen
targeted mutation 1, Deltagen
MGI:3604457
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
B3galt2tm1Dgen/B3galt2tm1Dgen involves: 129P2/OlaHsd * C57BL/6 MGI:3606681


Genotype
MGI:3606681
hm1
Allelic
Composition
B3galt2tm1Dgen/B3galt2tm1Dgen
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
B3galt2tm1Dgen mutation (1 available); any B3galt2 mutation (16 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• spend significantly more time immobile in the Tail Suspension test, indicating a possible depression-like phenotype
• spend significantly more time in the central region of the open field, indicating decreased anxiety
• exhibit enhanced startle responses to sound stimuli at 110 db and 120 db
• exhibit impaired activity on the rotarod test, falling from accelerating rotarod at slower speeds than wildtype
• exhibit an increase in total distance traveled in the Open Field test

growth/size/body
• body weight of homozygous males is decreased compared to controls





Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/24/2023
MGI 6.22
The Jackson Laboratory