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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Erap1tm1Dgen
targeted mutation 1, Deltagen
MGI:3604456
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Erap1tm1Dgen/Erap1tm1Dgen involves: 129P2/OlaHsd * C57BL/6 MGI:3606676


Genotype
MGI:3606676
hm1
Allelic
Composition
Erap1tm1Dgen/Erap1tm1Dgen
Genetic
Background
involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Erap1tm1Dgen mutation (1 available); any Erap1 mutation (59 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
hematopoietic system
• 2 of 4 homozygotes exhibit atypical hyperplasia of the thymus gland at 300 days of age
• 2 of 4 homozygotes exhibit enlarged spleen, increased spleen weight, and increased spleen weight/body weight ratio at 300 days of age
• 2 of 4 homozygotes exhibit increased extramedullary hematopoiesis of the spleen at 300 days of age

immune system
• 2 of 4 homozygotes exhibit atypical hyperplasia of the thymus gland at 300 days of age
• 2 of 4 homozygotes exhibit enlarged spleen, increased spleen weight, and increased spleen weight/body weight ratio at 300 days of age

renal/urinary system
• the size and weight of the kidney is increased in 2 of 2 males at 300 days of age

endocrine/exocrine glands
• 2 of 4 homozygotes exhibit atypical hyperplasia of the thymus gland at 300 days of age

growth/size/body
• the size and weight of the kidney is increased in 2 of 2 males at 300 days of age
• 2 of 4 homozygotes exhibit enlarged spleen, increased spleen weight, and increased spleen weight/body weight ratio at 300 days of age





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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory