All Phenotypes Prdm9<+> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Prdm9⁺
wild type
MGI:3588543

Summary

2 genotypes

Allelic Composition	Prdm9^em2Kpgn/Prdm9⁺
Genetic Background	C57BL/6J-Prdm9^em2Kpgn/Kpgn

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prdm9^em2Kpgn mutation (1 available); any Prdm9 mutation (46 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

cellular

decreased oocyte number ( J:299008 )

• heterozygotes have an intermediate phenotype with fewer than normal oocytes but more than those found in homozygotes

reproductive system

decreased oocyte number ( J:299008 )

• heterozygotes have an intermediate phenotype with fewer than normal oocytes but more than those found in homozygotes

Allelic Composition	Prdm9^M1045Lja/Prdm9⁺
Genetic Background	involves: C57BL/6J * DBA

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Prdm9^M1045Lja mutation (0 available); any Prdm9 mutation (46 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

Incomplete dominance with spermatogenic block in Prdm9^M1045Lja/Prdm9⁺ mice or germ cell loss in Prdm9^M1045Lja/Prdm9^M1045Lja mice

reproductive system

abnormal spermatid morphology ( J:179895 )

• absence of elongated spermatids in the tubules

decreased male germ cell number ( J:179895 )

• absence of sperm in the epididymides

azoospermia ( J:179895 )

small testis ( J:179895 )

• mild hypogonadism in males

abnormal spermiogenesis ( J:179895 )

• late spermatogenic block precluding spermiogenesis

endocrine/exocrine glands