Phenotypes associated with this allele

• Allele Symbol: St8sia4^tm1Crem
• Allele Name: targeted mutation 1, Harold Cremer
• Allele ID: MGI:3582251
• Summary: 1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	St8sia4^tm1Crem/St8sia4^tm1Crem	involves: 129P2/OlaHsd * C57BL/6J	MGI:3582290

Genotype
MGI:3582290

hm1

• Allelic Composition: St8sia4^tm1Crem/St8sia4^tm1Crem
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

reduced long-term potentiation ( J:63481 )

• adult, but not young, homozygous null mice exhibit impaired long term potentiation in hippocampal CA1 synapses but not CA3 synapses

reduced long-term depression ( J:63481 )

• adult, but not young, homozygous null mice exhibit impaired long term depression in hippocampal CA1 synapses