All Phenotypes Tg(Tcra,Tcrb)1Mcd MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Tg(Tcra,Tcrb)1Mcd
transgene insertion 1, Hugh O McDevitt
MGI:3581980

Summary

1 genotype

Jump to	Allelic Composition	Genetic Background	Genotype ID
cx1	Tg(LCK-NFKBIA)5Dwb/? Tg(Tcra,Tcrb)1Mcd/?	involves: BALB/c * C57BL/6 * DBA/2	MGI:3835055

Allelic Composition	Tg(LCK-NFKBIA)5Dwb/? Tg(Tcra,Tcrb)1Mcd/?
Genetic Background	involves: BALB/c * C57BL/6 * DBA/2

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(LCK-NFKBIA)5Dwb mutation (2 available)
Tg(Tcra,Tcrb)1Mcd mutation (1 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

immune system

decreased interferon-gamma secretion ( J:145531 )

• mutant T cells produce very little IFN-gamma when transferred into host that is immunized with hemagglutinin

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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