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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID
Lrp4dan
digitation anormale
MGI:3580702
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
Lrp4dan/Lrp4dan 129S2/SvPas-Lrp4dan MGI:3623728


Genotype
MGI:3623728
hm1
Allelic
Composition
Lrp4dan/Lrp4dan
Genetic
Background
129S2/SvPas-Lrp4dan
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lrp4dan mutation (1 available); any Lrp4 mutation (97 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
limbs/digits/tail
• variable brachydactyly seen on all four limbs
• duplication of digits along the dorsoventral axis
• variable syndactyly seen on all four limbs
• typically involves fusion of 2 or 3 adjacent segments along the anteroposterior axis

growth/size/body

behavior/neurological
• displayed by adults
• females and males are fertile but females sometimes fail to nurse their pups

craniofacial
N
• no tooth abnormalities are seen

integument
• adults have dull fur
• nails are often abnormally shaped or placed but are never fused





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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory