All Phenotypes Agrn<tm5Jrs> MGI Mouse

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Phenotypes associated with this allele

Allele Symbol
Allele Name
Allele ID

Agrn^tm5Jrs
targeted mutation 5, Joshua R Sanes
MGI:3578923

Summary

2 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
hm1	Agrn^tm5Jrs/Agrn^tm5Jrs	involves: 129S1/Sv * 129X1/SvJ * FVB/N	MGI:5692157
cx2	Agrn^tm5Jrs/Agrn^tm5Jrs Tg(APPswe,PSEN1dE9)85Dbo/?	involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 * FVB/N	MGI:5692159

Allelic Composition	Agrn^tm5Jrs/Agrn^tm5Jrs
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Agrn^tm5Jrs mutation (0 available); any Agrn mutation (101 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:220073 )

N	• Agrn gene is expressed primarily in CNS neurons • no abnormal phenotypes • in particular, no ataxia, seizures, or spasticity

mortality/aging

mortality/aging ( J:220073 )

N	• normal lifespan

Allelic Composition	Agrn^tm5Jrs/Agrn^tm5Jrs Tg(APPswe,PSEN1dE9)85Dbo/?
Genetic Background	involves: 129S1/Sv * 129X1/SvJ * C3H * C57BL/6 * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Agrn^tm5Jrs mutation (0 available); any Agrn mutation (101 available)
Tg(APPswe,PSEN1dE9)85Dbo mutation (6 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

nervous system phenotype ( J:220073 )

N	• Agrn gene is expressed primarily in CNS neurons • no affect on amyloid beta

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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