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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Arhgap29+
wild type
MGI:3576379
Summary 4 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
ht1
 		\Arhgap29em1(IMPC)J/\Arhgap29+ C57BL/6NJ-Arhgap29em1(IMPC)J/J MGI:6150842
ht2
 		\Arhgap29em1(IMPC)J/\Arhgap29+ C57BL/6NJ-Arhgap29em1(IMPC)J/J MGI:6261893
ht3
 		\Arhgap29tm1Murr/\Arhgap29+ C57BL/6NJ-Arhgap29tm1Murr/GrsrJ MGI:6150829
cx4
 		\Arhgap29tm1Murr/\Arhgap29+
\Mafbtm1.2Mardu/\Mafb+ 		involves: C57BL/6 * C57BL/6J * C57BL/6N * CBA MGI:7256936


Genotype
MGI:6150842
ht1
Allelic
Composition		 \Arhgap29em1(IMPC)J/\Arhgap29+
Genetic
Background		 C57BL/6NJ-Arhgap29em1(IMPC)J/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arhgap29em1(IMPC)J mutation (1 available); any Arhgap29 mutation (47 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
abnormal oral epithelium morphology ( J:257248 )
• intraoral epithelial adhesions are found at E14.5, but fewer than are found in mice heterozygous for the em1Murr allele

digestive/alimentary system
abnormal oral epithelium morphology ( J:257248 )
• intraoral epithelial adhesions are found at E14.5, but fewer than are found in mice heterozygous for the em1Murr allele

growth/size/body
palatal shelf fusion with tongue or mandible ( J:257248 )
abnormal oral epithelium morphology ( J:257248 )
• intraoral epithelial adhesions are found at E14.5, but fewer than are found in mice heterozygous for the em1Murr allele




Genotype
MGI:6261893
ht2
Allelic
Composition		 \Arhgap29em1(IMPC)J/\Arhgap29+
Genetic
Background		 C57BL/6NJ-Arhgap29em1(IMPC)J/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arhgap29em1(IMPC)J mutation (1 available); any Arhgap29 mutation (47 available)
Data Sources
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear

homeostasis/metabolism




Genotype
MGI:6150829
ht3
Allelic
Composition		 \Arhgap29tm1Murr/\Arhgap29+
Genetic
Background		 C57BL/6NJ-Arhgap29tm1Murr/GrsrJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arhgap29tm1Murr mutation (0 available); any Arhgap29 mutation (47 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
craniofacial
failure of palatal shelf elevation ( J:257248 )
• at E14.5 palatal shelves are elevated in only 72% of heterozygotes compared with 100% of wild-type controls
abnormal oral epithelium morphology ( J:257248 )
• intraoral epithelial contacts, including palatal shelf to tongue adhesions and tooth bud adhesions, are found in 75% of heterozygotes at E13.5 and 52% of heterozygotes at E14.5, but none in wild-type sibling controls, and by E18.5 the palates of heterozygotes are well-formed indicating and allow complete palatogenesis

embryo
abnormal periderm morphology ( J:257248 )
• the sites of some oral epithelial adhesions have flat periderm nuclei and the periderm layer is reported to be occossionally discontinuous or disorganized

digestive/alimentary system
failure of palatal shelf elevation ( J:257248 )
• at E14.5 palatal shelves are elevated in only 72% of heterozygotes compared with 100% of wild-type controls
abnormal oral epithelium morphology ( J:257248 )
• intraoral epithelial contacts, including palatal shelf to tongue adhesions and tooth bud adhesions, are found in 75% of heterozygotes at E13.5 and 52% of heterozygotes at E14.5, but none in wild-type sibling controls, and by E18.5 the palates of heterozygotes are well-formed indicating and allow complete palatogenesis

growth/size/body
failure of palatal shelf elevation ( J:257248 )
• at E14.5 palatal shelves are elevated in only 72% of heterozygotes compared with 100% of wild-type controls
palatal shelf fusion with tongue or mandible ( J:257248 )
abnormal oral epithelium morphology ( J:257248 )
• intraoral epithelial contacts, including palatal shelf to tongue adhesions and tooth bud adhesions, are found in 75% of heterozygotes at E13.5 and 52% of heterozygotes at E14.5, but none in wild-type sibling controls, and by E18.5 the palates of heterozygotes are well-formed indicating and allow complete palatogenesis




Genotype
MGI:7256936
cx4
Allelic
Composition		 \Arhgap29tm1Murr/\Arhgap29+
\Mafbtm1.2Mardu/\Mafb+
Genetic
Background		 involves: C57BL/6 * C57BL/6J * C57BL/6N * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Arhgap29tm1Murr mutation (0 available); any Arhgap29 mutation (47 available)
Mafbtm1.2Mardu mutation (0 available); any Mafb mutation (20 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
embryo phenotype ( J:311539 )
N
• mice born at normal Mendelian ratios

skeleton
skeleton phenotype ( J:311539 )
N
• normal palatogenesis




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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory