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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Bmpr2tm1.2Enl
targeted mutation 1.2, En Li
MGI:3574813
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Bmpr2tm1.2Enl/Bmpr2tm1.2Enl involves: 129S4/SvJae * C57BL/6 MGI:3574956
cn2
 		Bmpr2tm1.1Enl/Bmpr2tm1.2Enl
H2az2Tg(Wnt1-cre)11Rth/H2az2+ 		involves: 129S4/SvJae * C57BL/6J * CBA/J MGI:5558941


Genotype
MGI:3574956
hm1
Allelic
Composition		 Bmpr2tm1.2Enl/Bmpr2tm1.2Enl
Genetic
Background		 involves: 129S4/SvJae * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmpr2tm1.2Enl mutation (0 available); any Bmpr2 mutation (46 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging

growth/size/body
embryonic growth retardation ( J:97109 )
• exhibit severe growth retardation at E7.5

embryo
embryonic growth retardation ( J:97109 )
• exhibit severe growth retardation at E7.5




Genotype
MGI:5558941
cn2
Allelic
Composition		 Bmpr2tm1.1Enl/Bmpr2tm1.2Enl
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Genetic
Background		 involves: 129S4/SvJae * C57BL/6J * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmpr2tm1.1Enl mutation (1 available); any Bmpr2 mutation (46 available)
Bmpr2tm1.2Enl mutation (0 available); any Bmpr2 mutation (46 available)
H2az2Tg(Wnt1-cre)11Rth mutation (2 available); any H2az2 mutation (25 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
nervous system phenotype ( J:206541 )
N
• mice exhibit normal maxillary and mandibular branches of the trigeminal nerve
abnormal ophthalmic nerve morphology ( J:206541 )
• stunted and prematurely branched at E11.5




Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory