Phenotypes associated with this allele

• Allele Symbol: Rnpc3⁺
• Allele Name: wild type
• Allele ID: MGI:3574078
• Summary: 3 genotypes

Jump to	Allelic Composition	Genetic Background	Genotype ID
ht1	Rnpc3^tm1a(EUCOMM)Wtsi/Rnpc3^+	involves: C57BL/6N	MGI:6276266
ht2	Rnpc3^tm1b(EUCOMM)Wtsi/Rnpc3^+	involves: C57BL/6N	MGI:6276269
cn3	Ndor1^Tg(UBC-cre/ERT2)1Ejb/Ndor1^+ Rnpc3^tm1c(EUCOMM)Wtsi/Rnpc3^+	involves: 129S/SvEv * C57BL/6 * C57BL/6N	MGI:6276274

Genotype
MGI:6276266

ht1

• Allelic Composition: Rnpc3^{tm1a(EUCOMM)Wtsi}/Rnpc3⁺
• Genetic Background: involves: C57BL/6N
• Cell Lines: EPD0441_1_B10

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

normal phenotype

no abnormal phenotype detected ( J:267519 )

• heterozygotes are viable, fertile, phenotypically normal and exhibit a normal lifespan relative to control littermates

Genotype
MGI:6276269

ht2

• Allelic Composition: Rnpc3^{tm1b(EUCOMM)Wtsi}/Rnpc3⁺
• Genetic Background: involves: C57BL/6N
• Cell Lines: EPD0441_1_B10

normal phenotype

no abnormal phenotype detected ( J:267519 )

• adult heterozygotes are fertile, phenotypically normal, and exhibit a normal lifespan with no gross skeletal or growth defects or differences in pituitary gland weight relative to control littermates

Genotype
MGI:6276274

cn3

• Allelic Composition: Ndor1^{Tg(UBC-cre/ERT2)1Ejb}/Ndor1⁺; Rnpc3^{tm1c(EUCOMM)Wtsi}/Rnpc3⁺
• Genetic Background: involves: 129S/SvEv * C57BL/6 * C57BL/6N
• Cell Lines: EPD0441_1_B10

normal phenotype

no abnormal phenotype detected ( J:267519 )

• tamoxifen-treated adult mice appear phenotypically normal with no significant weight loss relative to control mice