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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		MrasGt(OST108223)Lex
gene trap OST108223, Lexicon Genetics
MGI:3530902
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		MrasGt(OST108223)Lex/MrasGt(OST108223)Lex B6;129S5-MrasGt(OST108223)Lex/Ieg MGI:5428683
hm2
 		MrasGt(OST108223)Lex/MrasGt(OST108223)Lex involves: 129S5/SvEvBrd * C57BL/6 MGI:3701854


Genotype
MGI:5428683
hm1
Allelic
Composition		 MrasGt(OST108223)Lex/MrasGt(OST108223)Lex
Genetic
Background		 B6;129S5-MrasGt(OST108223)Lex/Ieg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
MrasGt(OST108223)Lex mutation (2 available); any Mras mutation (98 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased B cell number ( J:82809 )
• a decreased mean percentage of peripheral blood B cells is seen in the homozygous mutant mice compared to controls

immune system
decreased B cell number ( J:82809 )
• a decreased mean percentage of peripheral blood B cells is seen in the homozygous mutant mice compared to controls




Genotype
MGI:3701854
hm2
Allelic
Composition		 MrasGt(OST108223)Lex/MrasGt(OST108223)Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
MrasGt(OST108223)Lex mutation (2 available); any Mras mutation (98 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:112961 )
• mice are not morphologically different from wild-type mice and have normal brain morphology and function




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory