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Phenotypes associated with this allele
Allele Symbol
Allele Name
Allele ID 		Anxa4Gt(OST134786)Lex
gene trap OST134786, Lexicon Genetics
MGI:3530283
Summary 2 genotypes
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Anxa4Gt(OST134786)Lex/Anxa4Gt(OST134786)Lex involves: 129S5/SvEvBrd MGI:3783436
hm2
 		Anxa4Gt(OST134786)Lex/Anxa4Gt(OST134786)Lex involves: 129S5/SvEvBrd * C57BL/6 MGI:3783424


Genotype
MGI:3783436
hm1
Allelic
Composition		 Anxa4Gt(OST134786)Lex/Anxa4Gt(OST134786)Lex
Genetic
Background		 involves: 129S5/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Anxa4Gt(OST134786)Lex mutation (2 available); any Anxa4 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
renal/urinary system phenotype ( J:133525 )
N
• bladder morphology and uroepithelial ultrastructure is indistinguishable from wild-type controls
• barrier function, membrane trafficking in response to hydrostatic pressure, void volumes and intrabladder pressures are similar to controls




Genotype
MGI:3783424
hm2
Allelic
Composition		 Anxa4Gt(OST134786)Lex/Anxa4Gt(OST134786)Lex
Genetic
Background		 involves: 129S5/SvEvBrd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Anxa4Gt(OST134786)Lex mutation (2 available); any Anxa4 mutation (22 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
abnormal maternal nurturing ( J:87727 )
• females often do not care for their pups
• pups are fostered to wild-type mothers in order for them to survive




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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory